
Draxxin Dosage for Cattle: A Comprehensive Guide
Draxxin, a tulathromycin-based solution, effectively treats respiratory diseases in cattle and swine; a standard dosage is 2.5 mg per kg, or 1.1 mL per 100 lbs body weight.
Understanding Draxxin and its Use in Cattle
Draxxin (tulathromycin) is a macrolide antibiotic specifically formulated for use in both cattle and swine, primarily targeting respiratory diseases. It’s a valuable tool for livestock producers aiming to manage conditions like bovine respiratory disease (BRD) and swine respiratory disease (SRD). The medication is administered via subcutaneous injection, offering a convenient method for delivering the antibiotic directly into the animal’s system.

Understanding the correct dosage is crucial for effective treatment and to minimize the risk of antibiotic resistance. A typical Draxxin dosage is 2.5 mg per kg of body weight, which translates to approximately 1.1 mL per 100 lbs of body weight. This standardized approach ensures consistent and reliable results when addressing respiratory challenges in cattle populations. Resources like Valley Vet and EntirelyPets Rx provide detailed drug facts sheets and dosage information.
Proper administration and adherence to withdrawal times are also essential components of responsible Draxxin use.
What is Tulathromycin?
Tulathromycin is a macrolide antibiotic belonging to a class of antimicrobials known for their effectiveness against a range of bacterial infections. Specifically, it’s utilized in veterinary medicine to combat respiratory diseases in both cattle and swine. Developed by Zoetis Animal Health, tulathromycin functions by inhibiting bacterial protein synthesis, effectively halting bacterial growth and allowing the animal’s immune system to overcome the infection.
As the active ingredient in Draxxin, tulathromycin is administered through subcutaneous injection. Its primary targets include Mannheimia haemolytica, Pasteurella multocida, and Histophilus somni – common pathogens responsible for bovine respiratory disease (BRD). The concentration within Draxxin is 100mg per ml, dictating precise dosage calculations based on the animal’s weight.
Understanding tulathromycin’s mechanism and application is vital for responsible antibiotic stewardship and ensuring optimal animal health outcomes. Dosage guidelines, such as 2.5 mg/kg, are crucial for maximizing efficacy.
Approved Uses of Draxxin in Cattle
Draxxin (tulathromycin) is primarily approved for the treatment and control of respiratory disease in cattle, specifically targeting infections caused by key bacterial pathogens. These include Mannheimia haemolytica, Pasteurella multocida, and Histophilus somni, all frequent contributors to Bovine Respiratory Disease (BRD); BRD manifests in various forms, impacting growth, feed efficiency, and overall animal welfare.
Beyond treatment, Draxxin also aids in controlling the spread of these infections within a herd. It’s indicated for use in both beef and dairy cattle, offering a versatile solution for respiratory challenges. The injectable solution is designed for subcutaneous administration, ensuring effective drug delivery and absorption.
Proper application, adhering to the recommended dosage of 2.5 mg/kg (or 1.1 mL per 100 lbs), is essential for maximizing therapeutic benefits and minimizing the risk of antibiotic resistance. Always consult veterinary guidance for specific case management.
Draxxin Dosage Calculation: The Core Principle
The fundamental principle behind Draxxin dosage calculation revolves around accurately determining the animal’s body weight and then applying the prescribed concentration of tulathromycin. The standard dosage is universally recognized as 2.5 mg of tulathromycin per kilogram of body weight. However, for practical application in cattle handling, a conversion to pounds is often preferred.
This conversion simplifies the process for ranchers and veterinarians accustomed to working with weight in pounds. The equivalent dosage translates to approximately 1.1 mL of Draxxin solution per 100 lbs of body weight. This ratio allows for quick and efficient dosage estimation directly in the field.
Accurate weight estimation is paramount; underdosing can lead to treatment failure, while overdosing increases the risk of adverse effects and contributes to antibiotic resistance. Utilizing scales whenever possible is highly recommended for precise calculations.
Standard Draxxin Dosage: 2.5 mg/kg
The cornerstone of Draxxin administration for cattle is the standardized dosage of 2.5 milligrams of tulathromycin per kilogram of body weight. This dosage has been rigorously tested and approved for the treatment and control of bovine respiratory disease (BRD), ensuring efficacy when administered correctly. It’s crucial to understand this metric as the foundation for all dosage calculations.

This concentration is consistently found within the Draxxin injectable solution, containing 100 mg of tulathromycin per milliliter. Therefore, calculating the appropriate volume to administer requires a direct correlation between the animal’s weight in kilograms and the solution volume.
Veterinarians and livestock handlers rely on this standard to provide consistent and effective treatment. Adhering to this dosage minimizes the risk of under-treatment and helps mitigate the development of antibiotic resistance, a growing concern in veterinary medicine.
Converting Kilograms to Pounds for Dosage
While the standard Draxxin dosage is expressed in milligrams per kilogram (mg/kg), many cattle producers are more familiar with weight measurements in pounds (lbs). Therefore, accurate conversion between these units is essential for precise dosage calculation. The conversion factor is approximately 2.20462 pounds per kilogram.
To convert a cattle’s weight from pounds to kilograms, divide the weight in pounds by 2.20462. Conversely, to convert from kilograms to pounds, multiply the weight in kilograms by 2.20462. This ensures the correct amount of Draxxin is administered, maximizing treatment effectiveness.
Many resources, including product inserts and online dosage calculators, provide this conversion factor. Utilizing these tools minimizes calculation errors. Remember, accurate weight estimation is paramount; using scales whenever possible is highly recommended for optimal Draxxin dosage.
Dosage Based on Cattle Weight (Specific Examples)
Calculating Draxxin dosage becomes simpler with specific weight examples. Remember the core principle: 2.5 mg/kg or 1.1 mL per 100 lbs of body weight. These examples illustrate practical application for common cattle weights.

For a 500 lb calf, the calculation is (500 lbs / 100 lbs) * 1.1 mL = 5.5 mL of Draxxin. An 800 lb steer requires (800 lbs / 100 lbs) * 1.1 mL = 8.8 mL. Finally, a 1000 lb mature cow needs (1000 lbs / 100 lbs) * 1.1 mL = 11 mL.
These calculations assume a standard Draxxin concentration of 100 mg/mL. Always double-check the product label for concentration verification. Precise dosing is crucial for therapeutic efficacy and minimizing the risk of antibiotic resistance. Utilizing a calibrated syringe is also highly recommended for accurate administration.
Draxxin Dosage for 500 lb Cattle
Determining the correct Draxxin dosage for 500 lb cattle is straightforward using the established guideline of 1.1 mL per 100 lbs of body weight. For a calf weighing 500 lbs, the calculation involves dividing the animal’s weight by 100, then multiplying by the dosage volume.
Therefore, (500 lbs / 100 lbs) * 1.1 mL = 5.5 mL of Draxxin injectable solution. This equates to a total of 5.5 mg of tulathromycin being administered. Ensure accurate measurement using a calibrated syringe to deliver the precise dose.
This dosage is intended as a single, subcutaneous injection. Always confirm the product concentration (typically 100 mg/mL) and adhere to the veterinarian’s instructions. Proper administration and dosage are vital for effective treatment and responsible antibiotic use in cattle.
Draxxin Dosage for 800 lb Cattle

Calculating the appropriate Draxxin dosage for 800 lb cattle relies on the standard recommendation of 1.1 mL per 100 lbs of body weight. To determine the correct volume, divide the cattle’s weight by 100, and then multiply the result by the dosage rate.
In this case, (800 lbs / 100 lbs) * 1.1 mL = 8.8 mL of Draxxin injectable solution. This delivers a total of 8.8 mg of tulathromycin to the animal. Precise measurement with a calibrated syringe is crucial for accurate dosing.
This dosage is administered via a single, subcutaneous injection, typically in the neck region. Always verify the product’s concentration (usually 100 mg/mL) and strictly follow your veterinarian’s guidance. Correct dosage is essential for effective treatment and responsible antimicrobial stewardship in cattle.

Draxxin Dosage for 1000 lb Cattle
For 1000 lb cattle, determining the correct Draxxin dosage remains consistent with the established guideline of 1.1 mL per 100 lbs of body weight. This straightforward calculation ensures accurate administration of the antibiotic, crucial for effective treatment of respiratory disease.

To calculate, divide the cattle’s weight (1000 lbs) by 100, resulting in 10. Multiply this value by the dosage rate (1.1 mL) to obtain the total volume: (1000 lbs / 100 lbs) * 1.1 mL = 11 mL of Draxxin solution.
Administer this 11 mL dose via subcutaneous injection, preferably in the neck region, using a properly calibrated syringe. Always double-check the product concentration (typically 100 mg/mL) and adhere to your veterinarian’s specific instructions. Accurate dosing supports optimal animal health and responsible antibiotic use.
Administration of Draxxin: Subcutaneous Injection
Draxxin is specifically formulated for subcutaneous (SQ) administration in cattle. This method ensures optimal absorption and distribution of the tulathromycin, maximizing its therapeutic effect against respiratory pathogens. Proper technique is paramount for both animal welfare and drug efficacy.
Utilize a sterile, single-use syringe and needle appropriate for SQ injections – typically a 20-25 gauge, ½ to ¾ inch needle. Before injecting, gently lift the skin to create a tent-like structure. Insert the needle at a shallow angle, ensuring it lies flat under the skin, not in muscle tissue.

Slowly inject the calculated Draxxin dosage, observing for any signs of leakage or discomfort. After injection, gently massage the area to aid in drug dispersion. Always adhere to recommended withdrawal times and consult the product label or your veterinarian for specific guidance.

Injection Site and Technique
The preferred injection site for Draxxin in cattle is the neck region, specifically along the anterior third, avoiding major blood vessels and nerves. This area offers ample subcutaneous tissue for absorption and minimizes the risk of damaging underlying structures. Rotate injection sites with each subsequent administration to prevent localized irritation or tissue damage;
Prior to injection, thoroughly clean and disinfect the chosen site with an appropriate antiseptic solution. Using a sterile technique, gently tent the skin and insert a 20-25 gauge, ½ to ¾ inch needle at a shallow angle. Aspirate briefly to confirm you haven’t entered a blood vessel; if blood is observed, withdraw the needle and select a new injection site.
Administer the Draxxin dosage slowly and steadily, ensuring complete delivery. Gently massage the injection site post-injection to promote dispersion. Proper technique minimizes discomfort and maximizes drug effectiveness.
Important Considerations Before Administering Draxxin
Before administering Draxxin, carefully assess each animal’s health status and weight to ensure accurate dosage calculation – remember 2.5 mg/kg or 1.1 mL/100 lbs. Avoid using Draxxin in cattle exhibiting signs of systemic illness or severe stress, as their response to treatment may be compromised.
Always adhere to proper withdrawal times to prevent residues in meat or milk. Thoroughly review the product label for specific warnings and precautions. Consider the potential for developing antibiotic resistance with repeated or inappropriate use of Draxxin.
Ensure proper handling and storage of the product, maintaining refrigeration as directed. Consult with a veterinarian to determine if Draxxin is the most appropriate treatment option for the specific respiratory condition affecting your cattle, considering potential interactions with other medications.
Withdrawal Times for Draxxin Treated Cattle
Strict adherence to withdrawal times is crucial when using Draxxin in cattle to ensure food safety and prevent residues in consumable products. For cattle intended for slaughter, a withdrawal period of 28 days must be observed after the last administration of Draxxin.
Dairy cattle receiving Draxxin treatment require a withdrawal period of 72 hours (3 days) before milk can be legally used for human consumption. These withdrawal times are established to allow the drug to be fully metabolized and eliminated from the animal’s system.
Producers must meticulously document all Draxxin administrations, including date, dosage, and animal identification, to accurately track withdrawal periods. Failure to comply with these regulations can result in significant penalties and compromise public health. Always consult the product label and your veterinarian for the most up-to-date withdrawal information.
Potential Side Effects and Monitoring
While generally well-tolerated, Draxxin administration can occasionally cause transient local reactions at the injection site, such as mild swelling or discomfort. These reactions typically resolve within a few days without intervention. More rarely, cattle may exhibit signs of hypersensitivity, including facial swelling or difficulty breathing – requiring immediate veterinary attention.
Careful observation of treated animals is essential. Monitor cattle for any adverse reactions following Draxxin injection. Reduced appetite, lethargy, or changes in fecal consistency should be reported to a veterinarian.
Although serious side effects are uncommon, responsible antibiotic use necessitates vigilant monitoring. It’s crucial to remember that overuse of antibiotics can contribute to antimicrobial resistance. Proper dosage, adherence to withdrawal times, and careful observation are vital components of responsible Draxxin use.
Draxxin and Antibiotic Resistance
The increasing prevalence of antibiotic resistance is a significant concern in veterinary medicine, and Draxxin, like all antibiotics, contributes to this challenge. Prudent antibiotic stewardship is paramount to preserving the effectiveness of Draxxin and other crucial medications.
Overuse and misuse of antibiotics accelerate the development of resistant bacterial strains. Utilizing Draxxin only when necessary, based on accurate diagnoses and susceptibility testing when available, is vital. Adhering strictly to the recommended dosage – 2.5 mg/kg or 1.1 mL/100 lbs – minimizes selective pressure.
Implementing preventative health measures, such as vaccination and biosecurity protocols, can reduce the need for antibiotic intervention. Responsible use of Draxxin, coupled with proactive disease prevention, is essential for mitigating the risk of antibiotic resistance and safeguarding animal health for the future.
Where to Find Draxxin and Relevant Resources (PDFs)
Draxxin (tulathromycin) is primarily available through veterinary supply companies and licensed veterinarians. Valley Vet, EntirelyPets Rx, and Zoetis Animal Health are key distributors offering Draxxin injectable solution.

Accessing official product information is crucial for proper administration and understanding dosage guidelines. Zoetis, the manufacturer, provides detailed product inserts and safety data sheets (SDS) as downloadable PDFs on their website. These resources outline the 2.5 mg/kg (or 1.1 mL/100 lbs) dosage, administration instructions, and withdrawal times.
Livestock Rx and Safe.PharmacySwine also offer drug facts sheets and related documentation. Always consult with your veterinarian to ensure you have the most current information and to confirm the appropriate Draxxin dosage for your specific cattle and situation. Prioritize official sources for accurate guidance.